Sponsored Research Opportunity
Juvenile Diabetes Research Foundation
Site-Targeted Delivery of Therapeutics to Pancreatic Islet Endocrine Cell Types
- Program Information
- Letter of Intent Deadline:
TBA (last known deadline was August 30, 2012)
- Program Description
JDRF is soliciting Expressions of Interest (EOI)s for projects addressing the need for validated islet endocrinecell specific targets that could ultimately be useful in the development of cell site-targeted delivery for therapeutics or imaging.
To achieve this, JDRF is soliciting EOIs for proposals addressing aspects of the following:
- Unbiased identification and validation of islet-cell specific targets for therapeutic delivery, including, but not limited to: Genomics, Proteomics, Antibody screens, Aptamer screens, Peptoid screens
The EOIs must address the rationale behind the screen as well as the approach that will be taken to prioritize potential hits. The novel analysis of existing datasets will also be considered under this call.
- Further confirmation of suitability of known candidate islet endocrine-cell specific targets with in vitro and animal models of diabetes (i.e. physiology, pathology, impact of binding/perturbations on beta cell/islet/pancreas biology.
- Other opportunities from Juvenile Diabetes Research Foundation